In recent years, Prof. Chen focuses mainly on the development of multiscale, quantitative optical imaging technology at micro to macro scale from cell-animal-human level. The ultimate goal is to provide solutions to early detection and accurate diagnosis of cancers. The research contents include the theoretical methods, imaging systems, and biomedical applications, which have been linked together as the main research lines. Prof. Chen has been supported by the National Key R&D projects, the Major R&D Instruments projects of the NSFC, the Fok Ying-Tong Education Foundation of China, and so on. The total research fund reached 16 million RMB.

On-going Projects:

1. PI, General Program of the National Natural Science Foundation of China under Grant No. 81871397, Limited-angle and sparse sampling-based Raman-optical projection tomography, 2019.01.01-2022.12.31, 0.57 million.
2. PI, Subproject of the National Key R&D Program of China under Grant No. 2018YFC0910602, Research and development of high spatiotemporal resolution, high sensitivity, multi-scale, and multimodality molecular imaging technology for precise diagnosis and treatment of esophageal cancer, 2018.07.01-2020.12.31, 2.8845 million.
3. Co-PI, Secondary Subproject of the National Key R&D Program of China under Grant No. 2018YFC0910601, Development of molecular imaging probe with high specificity and high biosafety for esophageal cancer, 2018.07.01-2020.12.31, 0.9615 million.
4. PI, Youth Teacher Fund of Fok-Ying Tong Education Foundation of China under Grant No. 11604, Signal enhancement and three-dimensional reconstruction for endoscopic Cerenkov luminescence imaging, 2018.03-2021.03, 0.174 million.
5. PI, The Youth Talent Support Program in Shaanxi Province, Multi-scale, multimodality biophotonics imaging, 2018.01.01-2020.12.31, 1 million
6. PI, Subproject of Major Scientific Research Instrument Development Project of National Natural Science Foundation of China under Grant No. 81627807, The development and clinical application of multimodality digestive endoscopy, 2017.01.01-2021.12.31, 2.2 million.

Recently Completed Projects:

1. PI, The Research Fund for Young Star of Science and Technology in Shaanxi Province under Grant No. 2018KJXX-018, Endoscopic radioluminescence imaging technology and 3D imaging method, 2018.01.01-2019.12.31, 0.1 million.
2. PI, The Best Funded Projects for the Scientific and Technological Activities for Excellent Overseas Researchers in Shaanxi Province under Grant No. 2017017, Bessel beam based spontaneous Raman projection tomography, 2018.01.01-2019.12.31, 0.05 million.
3. PI, General Program of National Natural Science Foundation of China under Grant No. 81571725, Three-dimensional quantification of tumor receptor by using multimodality imaging of radioluminescence-PET-CT, 2016.01.01-2019.12.31, 0.56 million.
4. PI, Natural Science Basic Research Plan in Shaanxi Province of China under Grant No. 2015JQ6249, Research on endoscopic Cerenkov luminescence tomographic method and signal enhanced techniques, 2015.01.01-2016.12.31, 0.02 million.
5. PI, Youth Program of the National Natural Science Foundation of China under Grant No. 81101083, Endoscopic tomography for Cerenkov luminescence imaging, 2012.01.01- 2014.12.31, 0.23 million.
6. PI, Open Project Program of the State Key Laboratory of Management and Control for Complex System in CAS under Grant No. 20120101, Development of the Endoscopic Cerenkov luminescence imaging system, 2012.12.01-2014.12.31, 0.06 million
7. PI, Fundamental Research Funds for the Central Universities (JB171202, JBG151206, NSIY061406, K5051210001).
8. Participant, Key Program of National Natural Science Foundation of China under Grant No. U1401255, Study on the key issues of surgery-assisted system for complex congenital heart diseases surgery with multimodality images fusion and visualization technology, 2015.01.01-2018.12.21, 0.968 million.
9. Participant, Subproject of Major Scientific Research Instrument Development Project of National Natural Science Foundation of China under Grant No. 81227901, Development of the optical-PET-CT multimodality imaging system, 2013.01.01-2017.12.31, 10 million (2 million).
10. Participant, Key Program of National Natural Science Foundation of China under Grant No. 81230033, Study of the key point in developing multimodal Radionuclide-Cerenkov fusion imaging, 2013.01.01-2017.12.31, 2.8 million.
11. Participant, Subproject of the Major Program of the National Natural Science Foundation of China under Grant No. 81090272, 2011.01.01-2014.12.31, 2.01 million (0.5 million).
12. Participant, Subproject of the Program of the National Basic Research and Development Program of China (973) under Grant No. 2011CB707702, Platform for multimodality image fusion and computing, 2011.01.01-2015.12.31, 0.93 million (0.2 million).
13. Participant, National Natural Science Foundation of China under Grant Nos., 30900334, 81000632, etc. during years of 2009-2012.