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代表性学术论文

 

2024

[1] Sijia Wu, Xinyu Qin, Liyu Huang*, The role of alternative polyadenylation in epithelial-mesenchymal transition of non-small cell lung cancer, Human Molecular Genetics, 2024, ddae001, . doi:10.1093/hmg/ddae001.

[2] Yun Zhang, Yubo Wang, Huanhuan Cheng, Fei Yan, Dingning Li, Dawei Song, Qiang Wang*, Liyu Huang*. EEG spectral slope: A reliable indicator for continuous evaluation of consciousness levels during propofol anesthesia.  Neuroimage,  2023, 283: 120426. doi: 10.1016/j.neuroimage.2023.120426. 

[3] Kexin Huang, Xi Liu, Zhaocan Zhang, Tiangang Wang, Haixia Xu, Qingxuan Li, Yuhao Jia, Liyu Huang, Pora Kim, Xiaobo Zhou*. AgeAnnoMO: a knowledgebase of multi-omics annotation for animal aging.  Nucleic Acids Research,  2024, 52: D822-D834. doi: 10.1093/nar/gkad884. 

 

2023

[1] Kexin Huang, Yun Zhang, Xiaori Shi, Zhiqin Yin, Weiling Zhao, Liyu Huang*, Fu Wang*, Xiaobo Zhou*. Cell-type specific alternative polyadenylation promotes oncogenic gene expression in non-small cell lung cancer progression,  Molecular Therapy-Nucleic Acids, 2023, 33:816-831.  doi:  10.1016/j.omtn.2023.08.005.

[2] Suping Cai, Zitong Guo, Xuwen Wang, Kexin Huang, Kai Yuan*, Liyu Huang*, Cortical thickness differences are associated with cellular component morphogenesis of astrocytes and excitatory neurons in nonsuicidal self-injuring youthCerebral Cortex, 2023, 33(3): 811-822.  doi: 10.1093/cercor/bhac103.  

[3] Kexin Huang,  Hoaran Gong,Jingjing Guan, Lingxiao Zhang, Changbao, Hu, Weiling Zhao, Liyu Huang, Wei Zhang, Para Kim*, Xiaobo Zhou*.  AgeAnno: a knowledgebase of single-cell annotation of aging in human,  Nucleic Acids Research,  2023, 51: D805-815. doi:  10.1093/nar/gkac847. 

[4] Kexin Huang,  Sijia Wu, Xiaotong Yang, Tiangang Wang, Xi Liu, Xiaobo Zhou* and Liyu Huang*.  CAFuncAPA: a knowledgebase for systematic functional annotations of APA events in human cancers. NAR Cancer,  2023,  5(1):  ZCAD004. doi: 10.1093/narcan/zcad004.   

[5]  Kexin Huang, Yun Zhang, Haoran Gong, Zhengzheng Qiao, Tiangang Wang, Weiling Zhao, Liyu Huang*, Xiaobo Zhou*.
Inferring evolutionary trajectories from crosssectional transcriptomic data to mirror lung adenocarcinoma progression.  PLOS Computational Biology, 2023, 19(5): e1011122. doi: 10.1371/journal.pcbi.1011122. 

[6] Sijia Wu, Zhiwei Fan, Pora Kim*, Liyu Huang*, Xiaobo Zhou*. The Integrative Studies on the Functional A-to-I RNA Editing Events in Human Cancers.  Genomics, Proteomics & Bioinformatics,  2023,  21(3):619-631.  doi: 10.1016/j.gpb. 2022.12.010. 

[7] Sijia Wu, Qiuping Xue, Xinyu Qin, Xiaoming Wu, Pora Kim, Jacqueline Chyr, Xiaobo Zhou*, Liyu Huang* The Potential Regulation of A-to-I RNA Editing on Genes in Parkinson’s Disease.  Genes,  2023, 14(4): 919.  doi:10.3390/genes14040919.  

[8] Sijia Wu, Qiuping Xue, Mengyuan Yang, Yanfei Wang, Pora Kim*, Xiaobo Zhou*, Liyu Huang*.  Genetic control of RNA editing in neurodegenerative disease, Briefings in Bioinformatics, 2023, 24(2), bbad007.  doi: 10.1093/bib/bbad007. 

 

2022

[1] Haidong Wang, Yun Zhang, Huanhuan Cheng, Fei Yan, Dawei Song, Qiang Wang*, Suping Cai*, Yubo Wang*, Liyu Huang*.  Selective corticocortical connectivity suppression during propofol-induced anesthesia in healthy volunteers,  Cognitive Neurodynamics,  2022, 16:1029-1043. doi: 10.1007/s11571-021-09775-x. 

[2] Suping Cai, Kexin Huang, Fan Yang, Xuwen Wang, Sijia Wu, Yubo Wang, Liyu Huang*.  Cortical Thickness Differences Are Associated With Chemical Synaptic Transmission Upregulated Genes in Degeneration of Mild Cognitive Impairment.  Frontiers in Aging Neuroscience, 2021, 13: Article 745381.  doi: 10.3389/fnagi.2021.745381. 

[3] Kexin Huang, Lifeng Yang, Yubo Wang, Liyu Huang, Xiaobo Zhou, Wei Zhang*.  Identification of non-small-cell lung cancer subtypes by unsupervised clustering of CT image features with distinct prognoses and gene pathway activities. Biomedical Signal Processing and Control,  2022, 76: 103643. doi: 10.1016/j.bspc.2022.103643. 

[4] Suping Cai, Fan Yang, Xuwen Wang, Sijia Wu, Liyu Huang*. Structural brain characteristics and gene co-expression analysis: A study with outcome label from normal cognition to mild cognitive impairment.  Neurobiology of Learning and Memory. 2022, 191: 107620.  doi: 10.1016/j.nlm.2022.107620. 

 

2021

[1] Suping Cai, Xuwen Wang, Fan Yang, Dihui Chen, Liyu Huang*.   Differences in Brain Structural Covariance Network Characteristics in Children and Adults With Autism Spectrum Disorder,  Autism Research,  2021, 14: 265–275.  doi: 10.1002/aur.2464.

[2] Sijia Wu, Jiachen Wang, Xinchao Zhu, Jacqueline Chyr, Xiaobo Zhou*, Xiaoming Wu*, Liyu Huang*. The Functional Impact of Alternative Splicing on the Survival Prognosis of Triple-negative Breast Cancer.  Frontiers in Genetics,  2021, 11: 604262.  doi: 10.3389/fgene.2020.6042622021. 

[3] Xue Zhao, Yubo Wang, Yun Zhang, Haidong Wang, Junchan Ren,  Fei Yan,  Dawei Song, Ruini Du, Qiang Wang*, Liyu Huang*.  Propofol-induced anesthesia alters corticocortical functional connectivity in the human brain: an EEG source space analysis.  Neuroscience Bulletin, 2021,37: 563-568.  doi: 10.1007/s12264-021-00633-8.

[4] Haidong Wang, Yubo Wang, Yun Zhang,  Zhen Dong, Fei Yan, Dawei Song, Qiang Wang* , Liyu Huang*. Differentiating propofol-induced altered states of consciousness using features of EEG microstates, Biomedical Signal Processing and Control,  2021, 64: 102316. doi: 10.1016 /j.bspc.2020.102316.

[5] Yiming Yu, Yubo Wang, Maoqing Yang, Meiping Huang, Jun Li, Qianjun Jia, Jian Zhuang, Liyu Huang*.  Evaluating the Severity of Aortic Coarctation in Infants Using Anatomic Features Measured on CTA, European Radiology, 2021, 31: 1216–1226.  doi: 10.1007/s00330-020-07238-1. 

[6] Yubo Wang, Chenghao Wan, Yun Zhang, Yu Zhou, Haidong Wang, Fei Yan, Dawei Song, Ruini Du, Qiang Wang*, Liyu Huang*.  Detecting Connected Consciousness During Propofol-Induced Anesthesia Using EEG Based Brain Decoding.  International Journal of Neural Systems, 2021,  Paper 2150021.  doi: 10.1142/S0129065721500210. 

[7] Kexin Huang, Yafei Kang, Zhongcheng Wu, Yubo Wang, Suping Cai, Liyu Huang*.  Asymmetrical alterations of grey matter among psychiatric disorders: A systematic analysis by voxelbased activation likelihood estimation.  Progress in Neuropsychopharmacology & Biological Psychiatry, 2021,  110:110322.  doi:10.1016/j.pnpbp.2021.110322.

[8] Xuwen Wang, Kexin Huang, Fan Yang, dihui Chen, Suping Cai*, Liyu Huang*.  Association between structural brain features and gene expression by weighted gene co-expression network analysis in conversion from MCI to AD.  Behavioural Brain Research,  2021, 410:113330.  doi: 10.1016/j.bbr.2021.113330. 

[9] Sijia Wu, Mengyuan Yang, Pora Kim, Xiaobo Zhou. ADeditome provides the genomic landscape of A-to-I RNA editing in Alzheimer’s disease, Briefings in Bioinformatics, 2021, 22(5), bbaa384.  doi: 10.1093/bib/bbaa384.

 

2020

[1] Yafei Kang, Wei Zhang, Yahui Lv, Suping Cai, Hanxiao Xu, Jijun Wang*, Liyu Huang*. Effects of the 5-HT2A and DRD3 genotypes on cortical morphology and functional connectivity density in drug-naïve first episode schizophrenia.   Schizophrenia Research,  2020, 216: 213-221. doi: 10.1016/j.schres.2019.11.058. 

[2] Tao Wang, Tingting Gao, Hua Guo, Yubo Wang, Xiaobo Zhou, Jie Tian, Liyu Huang*, Ming Zhang*. Preoperative prediction of parametrial invasion in early-stage cervical cancer with MRI-based radiomics nomogram. European Radiology, 2020, 30: 3585-3593. doi: 10.1007/s00330-019-06655-1. 

[3]  Kexin Huang, Yanyan Lin, Lifeng Yang, Yubo Wang, Suping Cai, Liaojun Pang,  Xiaoming Wu, Liyu Huang*. A multipredictor model to predict the conversion of mild cognitive impairment to Alzheimer’s disease by using a predictive nomogram. Neuropsychopharmacology,  2020, 45:358-366.  doi : 10.1038/s41386-019-0551-0. 

[4] Suping Cai, Yahui Lv, Kexin Huang, Wei Zhang, Qiang Wang, Liyu Huang* and Jijun Wang*.  Modulation on Glutamic Pathway of
Frontal-Striatum-Thalamus by rs11146020 and rs3813296 Gene Polymorphism in First-Episode Negative Schizophrenia.  Frontiers in Neuroscience, 2020, 14: 351. doi: 10.3389/fnins.2020.00351. 

[5] Yafei Kang, Kexin Huang, Yanyan Lin, Hanxiao Xu, Wei Zhang, Yahui Lv, Suping Cai, Liyu Huang*. Abnormalities of effective connectivity and white matter microstructure in the triple network in patients with Schizophrenia. Psychiatry Research,  2020, 290: 113019. doi: 10.1016/j.psychres.2020.113019. 

[6] Yahui Lv, Sijia Wu, Yanyan Lin, Xuwen Wang, Jijun Wang, Suping Cai*, Liyu Huang*. Association of rs1059004 polymorphism in the OLIG2 locus with functional brain network in first-episode negative schizophrenia.  Psychiatry Research: Neuroimaging, 2020, 303: 111130.  doi: 10.1016/j.pscychresns.2020.111130.

[7] Yanyan Lin, Kexin Huang, Hanxiao Xu, Zhengzheng Qiao, Suping Cai, Yubo Wang, Liyu Huang*.  Predicting the progression of mild cognitive impairment to Alzheimer's disease by using longitudinal magnetic resonance imaging-based dictionary learning.   Clinical Neurophysiology, 2020, 131(10): 2429-2439.  doi: 10.1016/j.clinph.2020.07.016.  

[8] Yun Zhang, Yubo Wang, Fei Yan, Dawei Song, Haidong Wang, Qiang Wang*, Liyu Huang*. Influence of pre-anesthesia dynamic frontal-parietal communication on individual susceptibility to propofol.  Clinical Neurophysiology, 2020,  131(11): 2566-2577.  doi: 10.1016/j.clinph.2020.07.018.  

 

2019

[1] Yafei Kang, Wei Zhang, Yahui Lv, Hanxiao Xu, Yanyan Lin, Suping Cai, Jijun Wang*, Liyu Huang*.  Genetic polymorphism in catechol‐O‐methyltransferase associated with the functional connectivity of frontostriatal circuits in first episode schizophrenia patients.  European Journal of Neuroscience,  2020, 51(10): 2134-2142.  doi: 10.1111/ejn.14659.

[2] Wei Zhang, Suping Cai, Kexin Huang, Yahui Lv, Yafei Kang, Qiang Wang, Liyu Huang*. Association between schizophrenia risk allele dosage of rs6994992 and whole-brain structural and functional characteristics. Psychiatry Research: Neuroimaging, 2019, 294: 110956. doi:10.1016/j.pscychresns.2019.05.005.

[3] Sijia Wu*, Xiaoming Wu, Jie Tian, Xiaobo Zhou, Liyu Huang*. PredictFP2: a new computational model to predict fusion peptide domain in all retroviruses. IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2020, 17(5): 1714-1720.  doi:10.1109/TCBB.2019.2898943.

[4] Yafei Kang, Kexin Huang, Yahui Lv, Wei Zhang, Suping Cai, Yubo Wang, Qiang Wang, Liyu Huang*, Jijun Wang*, Jie Tian*.Genetic contribution of catechol-O-methyltransferase in dorsolateral prefrontal cortex functional changes in the first episode schizophrenia. Behavioural Brain Research, 2019, 364:225-232.  doi: 10.1016/j.bbr.2019.02.012.

[5] Yun Zhang, chunshu Wang, Yubo Wang, Fei Yan, Qiang Wang, Liyu Huang*. Investigating dynamic functional network patterns after propofol-induced loss of consciousness. Clinical Neurophysiology, 2019, 130: 331~340. doi: 10.1016/j.clinph.2018.11.028. 

[6] Tao Wang, Tingting Gao, Jingbo Yang, Xuejiao Yan, Yubo Wang, Xiaobo Zhou, Jie Tian, Liyu Huang*, Ming Zhang*.Preoperative prediction of pelvic lymph nodes metastasis in early-stage cervical cancer using radiomics nomogram developed based on T2-weighted MRI and diffusion-weighted imaging, European Journal of Radiology, 2019, 114:128-135. doi:10.1016/j.ejrad.2019.01.003.

[7] Jingbo Yang, Tao Wang, Lifeng Yang, Yubo Wang, Hongmei Li, Xiaobo Zhou*, Weiling Zhao, Junchan Ren, Xiaoyong Li, Jie Tian, Liyu Huang*. Preoperative Prediction of Axillary Lymph Node Metastasis in Breast Cancer Using Mammography-Based Radiomics Method. Scientific Reports,  2019, 9: Article number: 4429. doi:10.1038/s41598-019-40831-z. 

[8] Suping Cai, Yahui Lv, Kexin Huang, Wei Zhang, Yafei Kang, Liyu Huang*, Jijun Wang*.  Association of rs1059004 polymorphism in the OLIG2 locus with whole-brain functional connectivity in first-episode schizophrenia.  Behavioural Brain Research, 2020,  379: 112392. doi:  10.1016/j.bbr.2019.112392. 

 

2018

[1]  Lifeng Yang, Jingbo Yang, Xiaobo Zhou, Liyu Huang*, Meiping Huang, Tao Wang, Jian Zhuang, Jie Tian*. Development a Radiomics Nomogram Based on the 2D and 3D CT Features to Predict the Survival of Non-Small Cell Lung Cancer Patients.  European Radiology,  2019, 29(5):2196-2206. doi:10.1007/s00330-018-5770-y.

[2] Suping Cai, Kexin Huang, Yafei Kang, Yuanyuan Jiang, Karen M.von Deneen, Liyu Huang*.  Potential biomarkers for distinguishing people with Alzheimer’s disease from cognitively intact elderly based on the rich-club hierarchical structure of white matter networks,  Neuroscience Research, 2019, 144:56-66.  doi:10.1016/j.neures. 2018.07.005.

[3] Yun Zhang, Fei Yan, Liu Wang, Yubo Wang, Chunshu Wang, Qiang Wang* and Liyu Huang*,  Cortical Areas Associated With Mismatch Negativity: A Connectivity Study Using Propofol Anesthesia. Frontiers in Human Neuroscience 2018,  12: Article number: 392. doi: 10.3389/fnhum.2018.00392.

[4] Yun Zhang, Yubo Wang, Chunshu Wang, Fei Ya, Qiang Wang*,  Liyu Huang*.  Investigation of hysteresis during anesthetic-induced unconsciousness by using brain functional networks,  Biomedical Signal Processing and Control,  2018, 46: 314-322.  doi: 10.1016/j.bspc.2018.07.008.

[5] Suping Cai, Yubo Wang,  Yafei Kang, Haidong Wang, Hyejin Kim, Karen M. von Deneen, Meiping Huang, Yuanyuan Jiang, and Liyu Huang*.  Differentiated Regional Homogeneity in Progressive Mild Cognitive Impairment: A Study With Post Hoc Label,  American Journal of Alzheimer’s Disease & Other Dementias,  2018, 33: 373-384.  doi: 10.1177/1533317518778513.

[6] Yafei Kang, Kexin Huang, Suping Cai, Haidong Wang, Jixin Liu, Yubo Wang, Yahui Lv, Wei Zhang, Qiang Wang, Liyu Huang*, Jijun Wang*, Jie Tian*.   Association between function and structure of the triple network and catechol-O-methyltransferase val158met polymorphism in the first episode schizophrenia. Neuroscience Letters, 2018,  687: 65-70. doi: 10.1016/j.neulet.2018.09.033. 

 

2017

[1] Suping Cai, Yanlin Peng, Tao Chong, Yun Zhang, Karen M.von. Deneen, Liyu Huang*.  Differentiated effective connectivity patterns of the executive control network in progressive MCI: a potential biomarker for predicting AD,  Current Alzheimer Research,  2017, 14(9): 937-950.  doi:10.2174/1567205014666170309120200.  

[2] Suping Cai, Yuanyuan Jiang, Yubo Wang, Xiaoming Wu, Junchan Ren, Min Seob Lee, Sunghoon Lee, Liyu Huang*. Modulation on brain gray matter activity and white matter integrity by APOE risk gene in cognitively intact elderly:a multimodal neuroimaging study. Behavioural Brain Research, 2017, 322:100-109. doi: 10.1016/j.bbr.2017.01.027.

[3] Suping Cai, Tao Chong, Yanlin Peng, Wenyue Shen, Jun Li, Karen M. von Deneen, Liyu Huang*. Altered functional brain networks in amnestic mild cognitive impairment: a resting-state fMRI study. Brain Imaging and Behavior. 2017, 11(3):619-631. doi: 10.1007/s11682-016-9539-0. 

[4] Zhongliang Yin, Jun Li, Yun Zhang, Aifeng Ren, Karen M. Von Meneen, Liyu Huang*, Functional brain network analysis of schizophrenic patients with positive and negative syndrome based on mutual information of EEG time series, Biomedical Signal Processing and Control, 2017, 31:331-338. doi: 10.1016/j.bspc.2016.08.013. 

 

 

2016

[1] Zhijie He, Quanbang Qiao, Jun Li, Meiping Huang, Shouping Zhu and Liyu Huang*, A fast method based on NESTA to accurately reconstruct CT image from highly undersampled projection measurements, Journal of X-Ray Science and Technology, 2016, 24:865-874. doi: 10.3233/XST-160597. 

[2] Dengfeng Huang, Aifeng Ren, Jing Shang, Qiao Lei, Yun Zhang, Zhongliang Yin, Jun Li, Karen M. von Deneen, Liyu Huang*, Combining Partial Directed Coherence and Graph Theory to Analyze Effective Brain Networks of Different Mental Tasks, Frontiers in Human Neuroscience, 2016, 10:235.  doi: 10.3389/fnhum.2016.00235.

[3] Jun Li, Minghao Dong, Aifeng Ren , Junchan Ren, Jinsong Zhang*, Liyu Huang*. Structural attributes of the temporal lobe predict face recognition ability in youth, Neuropsychologia, 2016, 84: 1-6. doi: 10.1016/j.neuropsychologia.2016.01.024.

[4] 乔全邦,黄力宇*,一种自适应的CT图像联合代数重建算法,西安电子科技大学学报,2016,43(3):73-78.

 

2015年以前

[1] Suping Cai , Tao Chong , Yun Zhang , Jun Li , Karen M. von Deneen , Junchan Ren , Minghao Dong* and Liyu Huang*, Altered functional connectivityof fusiform gyrus in subjects with amnestic mild cognitive impairment: a resting state fMRI study, Frontiers in Human Neuroscience, 2015, 9:471. doi: 10.3389/fnhum.2015.00471. 

[2] Suping Cai, Liyu Huang*, Jia Zou, Longlong Jing, Buzhong Zhai, Gongjun Ji, Karen M. von Deneen, et al. Changes in Thalamic Connectivity in the Early and Late Stages of Amnestic Mild Cognitive Impairment: A Resting-State Functional Magnetic Resonance Study from ADNI. PLoS ONE, 2015, 10(2), p e0115573.  doi: 10.1371/journal.pone.0115573. 

[3] 匡涛, 黄力宇*, 钟玉芳, 李超. 不完全投影图像重建的压缩感知算法, 西安电子科技大学学报,2015, 42(4): 106-112.

[4] Yufang Zhong, Liyu Huang*, Suping Cai, Yun Zhang, Karen M. von Deneen, Aifeng Ren, Junchan Ren. Altered effective connectivity patterns of the default mode network in Alzheimer’s disease: an fMRI study.  Neuroscience Letters, 2014, 578: 171-175. doi: 10.1016/j.neulet.2014.06.043. 

[5] Jianing Zheng, Liyu Huang*, Jing Zhao. Energy feature extraction and SVM classification of motor imagery induced electroencephalograms, Journal of Innovative Optical Health Sciences, 2012, 5(2): 1250006.  doi: 10.1142/S179354581250006X. 

[6] 晋琅, 黄力宇*, 郑佳宁, 张宇翔. 长周期前驱波的检测及其局域均值能量提取与分类, 电子学报,2012, 12: 2439-2445.

[7] Longlong Jing, Liyu Huang*, Dengfeng Huang, Jie Niu, Zheng Zhong. Amplitude of low frequency fluctuation at different frequency bands in early amnestic mild cognitive impairment: Results from ADNI, Journal of Innovative Optical Health Sciences, 2012, 5(1), 1150003.  doi: https://doi.org/10.1142/S1793545811500039. 

[8] Liyu Huang*, Zhao Jianxun, Singare Sekou, Wang Jue, Wang Yuemin. Discrimination of cerebral ischemic states using bispectrum analysis of EEG and artificial neural network,  Medical Engineering & Physics, 2007, 29(1): 1-7. doi: 10.1016/j.medengphy.2005.12.005.

[9] Liyu Huang*, Peng Yu, Fengchi Ju, Jingzhi Cheng. Prediction of response to incision using the mutual information of electroencephalograms during anaesthesia. Medical Engineering & Physics, 2003, 25 (4): 321~327.  doi: 10.1016/S1350-4533(02)00249-7.